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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 882584Generated: November 1, 2026

Hydrochloric Acid → HCID 71294511, compound

https://huagongshe.com/reaction/882584

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
ReactantHCID 66836374HCID 66836374—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 71294511HCID 71294511—

Reaction Steps

769 mg (1.86 mmol) of adamantan-1-ylmethyl N-(tert-butoxycarbonyl)-L-phenylalaninate (Intermediate 13) were dissolved in 25 ml of a 4 N solution of hydrogen chloride in dioxane and stirred at RT for 1 h. Subsequently, the reaction mixture was concentrated and the residue was dried under reduced pressure. 619 mg (95% of theory) of the title compound were obtained.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08992932B2
Source datasetuspto-grants-2015_03
ORD IDord-3bf3835649fa4eabac6db8c1a223ada0
Source noteuspto-grants-2015_03