HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 71294511, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 66836374 | HCID 66836374 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | HCID 71294511 | HCID 71294511 | — |
Reaction Steps
769 mg (1.86 mmol) of adamantan-1-ylmethyl N-(tert-butoxycarbonyl)-L-phenylalaninate (Intermediate 13) were dissolved in 25 ml of a 4 N solution of hydrogen chloride in dioxane and stirred at RT for 1 h. Subsequently, the reaction mixture was concentrated and the residue was dried under reduced pressure. 619 mg (95% of theory) of the title compound were obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08992932B2 |
| Source dataset | uspto-grants-2015_03 |
| ORD ID | ord-3bf3835649fa4eabac6db8c1a223ada0 |
| Source note | uspto-grants-2015_03 |