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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 882850Generated: October 31, 2026

Nitrate(1-), oxo- → HCID 66644693, compound

https://huagongshe.com/reaction/882850

Reaction equation

Participants

RoleNameHCIDCharge
ReactantNitrate(1-), oxo-HCID 3001380—
Reactant3-Amino-2-hydroxy-4-phenylbutanamideHCID 13882355—
ReactantHCID 66644887HCID 66644887—
ReactantHCID 178514248HCID 178514248—
ProductHCID 66644693HCID 66644693—

Reaction Steps

Coupling of (R)-5-oxo-1-(2,6-difluorobenzyl)-pyrrolidine-2-carboxylic acid with 3-amino-2-hydroxy-4-phenylbutanamide and oxidation of the resulting hydroxyamide intermediate to the corresponding ketoamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08236798B2
Source datasetuspto-grants-2012_08
ORD IDord-714a9abe3e624e36bda24660fbc9b699
Source noteuspto-grants-2012_08