2-Chloroethyl isocyanate → HCID 67027666, compound

HRID 882923Notes

Reaction equation

HRID 882923 reaction equation
[Cl:1][CH2:2][CH2:3][N:4]=[C:5]=[O:6].[CH2:7]([O:11][C:12]1[CH:17]=[CH:16][C:15]([NH2:18])=[CH:14][CH:13]=1)[CH:8]([CH3:10])[CH3:9]>C(OCC)C>[Cl:1][CH2:2][CH2:3][NH:4][C:5]([NH:18][C:15]1[CH:14]=[CH:13][C:12]([O:11][CH2:7][CH:8]([CH3:10])[CH3:9])=[CH:17][CH:16]=1)=[O:6]

Participants

4

Reactant 2

HCID 160352-Chloroethyl isocyanateHCID 50391404-Isobutoxyaniline

Product 1

HCID 67027666HCID 67027666, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

A solution of 2-chloroethyl isocyanate (15 g, 142 mmols) is added dropwise to a solution of 4-isobutoxy phenylamine (20 g, 121 mmols) in diethyl ether (100 mL) and stirred at RT for 1 h. The solid formed is collected by filtration and recrystallisation from ethanol affords the title compound.

Workup

  1. customThe solid formed
  2. filtrationis collected by filtration and recrystallisation from ethanol

Sources & evidence

ORD record
ord-1c517b78a4964979afa5860a7bc60935
Source dataset
uspto-grants-2012_08
Patent number
US08236808B2

Reaction notes

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