Phthalic Anhydride → HCID 178514958, compound

Participants

Reaction Conditions

Reaction Steps

1.2 3-Amino-pyrazole (278 mmol) is dissolved in acetic acid (240 ml) and isobenzofurane-1,3-dione (1 eq.) is added. The reaction solution is heated to 130° C. for 14 h. After cooling to RT, the precipitate is filtrated and washed with ethylacetate/heptane (1:1). 2-(1H-Pyrazol-3-yl)-isoindole-1,3-dione is obtained as a colourless powder; HPLC (Method B): 2.69 min; LC-MS (Method B): 1.360 min, 214.15 (M+H+).

Provenance & Evidence