HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromo-2-(trifluoromethoxy)iodobenzene → 7-(4-Bromo-2-trifluoromethoxy-phenyl)-1-ethyl-4,4,6-trimethyl-3,4-dihydro-1H-quinolin-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromo-2-(trifluoromethoxy)iodobenzene | HCID 2736422 | — |
| Reactant | 1-Ethyl-4,4,6-trimethyl-7-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-3,4-dihydro-1H-quinolin-2-one | HCID 21966443 | — |
| Product | 7-(4-Bromo-2-trifluoromethoxy-phenyl)-1-ethyl-4,4,6-trimethyl-3,4-dihydro-1H-quinolin-2-one | HCID 68665634 | — |
Reaction Steps
Compound 5B was prepared from Compound 5A and 4-bromo-1-iodo-2-trifluoromethoxy-benzene using a the conditions described for Example 1B. MS (electrospray): mass calculated for C21H21BrF3NO2, 455.07; m/z found 456.1 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08236819B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-deb208499f1f44c4b54ab226522095bc |
| Source note | uspto-grants-2012_08 |