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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 883949Generated: October 30, 2026

2-Aminothiazole → 4-chloro-3-nitro-N-(1,3-thiazol-2-yl)benzamide

https://huagongshe.com/reaction/883949

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-AminothiazoleHCID 2155—
Reactant4-Chloro-3-nitrobenzoyl chlorideHCID 123477—
Product4-chloro-3-nitro-N-(1,3-thiazol-2-yl)benzamideHCID 749218—

Reaction Steps

A mixture of 4-chloro-3-nitrobenzoyl chloride was reacted with Thiazol-2-ylamine to produce 4-Chloro-3-nitro-N-thiazol-2-yl-benzamide according to the procedure of Example 49A, which was treated sequentially using the procedures from Examples 53A and 53B to provide the title product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08236950B2
Source datasetuspto-grants-2012_08
ORD IDord-3a0b6da55567479aa4df25cdfe625bec
Source noteuspto-grants-2012_08