反应详情

The product from Example 7f was reacted with the product from Example 77A using the procedure from Example 73 substituting the product from Example 7f for the product from Example 9c and substituting the product from Example 77A for the product from Example 10B to provide the crude residue which was purified by trituration with methanol to provide the title compound. 1H NMR (300 MHz, DMSO-D6) δ ppm: 1.05-1.19 (m, 4 H), 2.22-2.41 (m, 1 H), 2.35 (s, 3 H), 7.05-7.31 (m, 7 H), 7.37 (s, 1 H), 7.58 (d, J=8.46 Hz, 1 H), 8.50 (s, 1 H), 8.65 (d, J=8.46 Hz, 1 H), 10.21 (s, 1 H); MS (ESI)+ m/z 385 (M+H)+.

1. customto provide the crude residue which
2. customwas purified by trituration with methanol