Thionyl Chloride → HCID 86615557, compound

HRID 883983Notes

Reaction equation

HRID 883983 reaction equation
[N+:1]([C:4]1[CH:5]=[C:6]([CH:10]=[CH:11][C:12]=1[S:13][C:14]1[CH:19]=[CH:18][C:17]([NH:20][C:21]([O:23][CH2:24][C:25]([Cl:28])([Cl:27])[Cl:26])=[O:22])=[CH:16][CH:15]=1)[C:7](O)=[O:8])([O-:3])=[O:2].S(Cl)([Cl:31])=O>CN(C)C=O>[Cl:26][C:25]([Cl:28])([Cl:27])[CH2:24][O:23][C:21](=[O:22])[NH:20][C:17]1[CH:18]=[CH:19][C:14]([S:13][C:12]2[CH:11]=[CH:10][C:6]([C:7]([Cl:31])=[O:8])=[CH:5][C:4]=2[N+:1]([O-:3])=[O:2])=[CH:15][CH:16]=1

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 67040552HCID 67040552, compound

Product 1

HCID 86615557HCID 86615557, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideCatalyst

Procedure

The product from Example 84a (2.0 g, 42.9 mmol) in thionyl chloride (10 mL) containing 1 drop of dimethylformamide and was heated to reflux for 3 hours. Cooled and concentrated under vacuum and dried under high vacuum overnight. The title compound was used without further purification.

Workup

  1. temperaturewas heated
  2. temperatureto reflux for 3 hours
  3. temperatureCooled
  4. concentrationconcentrated under vacuum
  5. customdried under high vacuum overnight
  6. customThe title compound was used without further purification

Sources & evidence

ORD record
ord-25d718b248b84419aaaba7b1dfc5026e
Source dataset
uspto-grants-2012_08
Patent number
US08236950B2

Reaction notes

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