反应详情

A solution of tert-butyl 3-(3-(phenylsulfonyl)quinolin-8-yl)azetidine-1-carboxylate (54 mg, 0.13 mmol) in CH2Cl2 (3 ml) was treated with hydrochloric acid (1M in ether, 0.3 ml) at 0° C. and then stirred at room temperature for 16 h. After concentration, the product was washed with EtOAc and dried in vacuo to give the title compound (45 mg, 98%) as a white solid.

1. concentrationAfter concentration
2. washthe product was washed with EtOAc
3. customdried in vacuo