反应详情

Thionyl chloride (4 mL) was added to a suspension of the benzothiazole-6-sulfonic acid (0.60 g, 2.79 mmol) in dichloroethane (15 mL) and the reaction mixture was heated at reflux and dimethylformamide (5 mL) was added to the reaction mixture to yield a clear solution. After 1.5 hr. at reflux, the solvent was removed in vacuo and excess HCl and thionyl chloride was chased by evaporation with dichloroethane.

1. temperaturethe reaction mixture was heated
2. temperatureat reflux
3. customto yield a clear solution
4. temperatureat reflux
5. customthe solvent was removed in vacuo and excess HCl and thionyl chloride
6. customwas chased by evaporation with dichloroethane