Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Formamide | HCID 713 | — |
| Reactant | HCID 178524203 | HCID 178524203 | — |
| Product | HCID 178513603 | HCID 178513603 | — |
Reaction Steps
5-[6-(2-Chlorophenyl)-2-oxo-1,2-dihydropyrimidin-4-yl]thiophene-2-carboxylic acid (100 mg, 0.30 mmol) was suspended in 1 mL of formamide. The reaction mixture was stirred for 30 minutes at 200° C. After cooling, the precipitate was filtered, dissolved in 1 mL dimethylformamide and purified by reverse phase HPLC. 30 mg of product were isolated.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08242129B2 |
|---|
| Source dataset | uspto-grants-2012_08 |
|---|
| ORD ID | ord-b48fd45743434e1686b4c13f38aac827 |
|---|
| Source note | uspto-grants-2012_08 |
|---|
