HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 59253027, compound → HCID 59253102, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 59253027 | HCID 59253027 | — |
| Solvent | 1,2-Dichloroethane | HCID 11 | — |
| Solvent | Trifluoroacetic acid | HCID 6422 | — |
| Product | HCID 59253102 | HCID 59253102 | — |
Reaction Steps
0.15 mg (3-Bromomethyl-4-{[(S)-cyclobutyl-(3-fluoro-phenyl)-methyl]-carbamoyl}-8-fluoro-1-oxo-1H-isoquinolin-2-yl)-propyl-carbamic acid tert-butyl ester was stirred at room temperature over night in 2 mL 1,2-dichloroethane and 2 mL trifluoroacetic acid. The reaction mixture was concentrated in vacuo to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242134B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-31efc7d8a42a4bd4b1a3ef49a47437b9 |
| Source note | uspto-grants-2012_08 |