Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 884754Generated: October 30, 2026

HCID 59253027, compound → HCID 59253102, compound

https://huagongshe.com/reaction/884754

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 59253027HCID 59253027—
Solvent1,2-DichloroethaneHCID 11—
SolventTrifluoroacetic acidHCID 6422—
ProductHCID 59253102HCID 59253102—

Reaction Steps

0.15 mg (3-Bromomethyl-4-{[(S)-cyclobutyl-(3-fluoro-phenyl)-methyl]-carbamoyl}-8-fluoro-1-oxo-1H-isoquinolin-2-yl)-propyl-carbamic acid tert-butyl ester was stirred at room temperature over night in 2 mL 1,2-dichloroethane and 2 mL trifluoroacetic acid. The reaction mixture was concentrated in vacuo to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242134B2
Source datasetuspto-grants-2012_08
ORD IDord-31efc7d8a42a4bd4b1a3ef49a47437b9
Source noteuspto-grants-2012_08