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HRID884808

反应详情

EQUATION

反应方程式

HRID 884808 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(C(=O)NC2CC2)cc1-n1ncc(C(=O)c2cccc(C#N)c2)c1N
HCID11338127

未命名化合物

结构：Br[Mg]C1CCCC1
HCID178419650

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(C(=O)NC2CC2)cc1-n1ncc(C(=O)C2CCCC2)c1N
HCID11772557

未命名化合物

PROCEDURE

实验过程

Similar procedure as in Example 17B except 3-[5-amino-4-(3-cyano-benzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methyl-benzamide was used in place of 3-(5-amino-4-cyano-imidazol-1-yl)-N-cyclopropyl-4-methyl-benzamide and cyclopentylmagnesium bromide was used in place of phenyl magnesium bromide. HPLC (4 minute 10-90 gradient) tR 2.54 min; MS m/z 353.19 [M+H]+.

WORKUP

后处理

  1. customHPLC (4 minute 10-90 gradient) tR 2.54 min