HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Methyl 3-Hydroxyphenylacetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Methanol | HCID 887 | — |
| Reactant | 3'-Hydroxyphenylacetic acid | HCID 12122 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | Methyl 3-Hydroxyphenylacetate | HCID 39129 | — |
Reaction Steps
3-Hydroxyphenylacetic acid (5 g, 32.9 mmol) in MeOH was treated with 4N HCl in 1,4-dioxane (3 mL) at 80° C. for 3 hours. The solution was concentrated to dryness to give the desired product as a yellow oil (5 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242145B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-49dc1924f75343daaf1434800ddd59d7 |
| Source note | uspto-grants-2012_08 |