(5-Benzyloxy-2-chloro-phenyl)-acetic acid ethyl ester → (2-Chloro-5-hydroxy-phenyl)-acetic acid ethyl ester

Participants

Reaction Conditions

Reaction Steps

(5-Benzyloxy-2-chloro-phenyl)-acetic acid ethyl ester (1.7 g, 5.6 mmol) was dissolved in EtOH (30 mL) and degassed with N2. 5% Palladium on carbon (1 g) was added, and the reaction was purged with H2 and then stirred under an H2 balloon at 50° C. overnight. The mixture was filtered and concentrated to give the desired product (1 g).

Provenance & Evidence