Benzyl Bromide → HCID 58237455, compound

HRID 885351Notes

Reaction equation

[CH2:1]([O:3][C:4](=[O:38])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([OH:12])=[C:8]([O:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][C:15]=2[CH2:24][N:25]2[C@H:29]([CH3:30])[C@H:28]([C:31]3[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=3)[O:27][C:26]2=[O:37])[CH:7]=1)[CH3:2].[CH2:39](Br)[C:40]1[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=1>>[CH2:1]([O:3][C:4](=[O:38])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH2:39][C:40]2[CH:45]=[CH:44][CH:43]=[CH:42][CH:41]=2)=[C:8]([O:13][C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:22])([F:23])[F:21])=[CH:16][C:15]=2[CH2:24][N:25]2[C@H:29]([CH3:30])[C@H:28]([C:31]3[CH:32]=[CH:33][CH:34]=[CH:35][CH:36]=3)[O:27][C:26]2=[O:37])[CH:7]=1)[CH3:2]

Participants

Reactant 2

HCID 7498Benzyl Bromide

HCID 58237618HCID 58237618, compound

Product 1

HCID 58237455HCID 58237455, compound

Procedure

Prepared according to the procedure described in Example 33, Step 3, using the following starting material: 2-{4-hydroxy-3-[2-((4R,5S)-4-methyl-2-oxo-5-phenyl-oxazolidin-3-ylmethyl)-4-trifluoromethyl-phenoxy]-phenyl}-acetic acid ethyl ester and benzyl bromide.

Workup

customPrepared

Sources & evidence

ORD record: ord-e8a6ec0448f9499f93ce0ce08db31a29
Source dataset: uspto-grants-2012_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08242145B2

Reaction notes

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