HuagongsheHuagongshe Chemistry Print Report · For research reference only
(1R,2S)-(+)-cis-1-Amino-2-indanol → (3-{2-[((1R,2S)-2-Hydroxy-indan-1-ylamino)-methyl]-4-trifluoromethyl-phenoxy}-4-methoxy-phenyl)-acetic acid ethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (1R,2S)-(+)-cis-1-Amino-2-indanol | HCID 2725045 | — |
| Reactant | [3-(2-Formyl-4-trifluoromethyl-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester | HCID 58237587 | — |
| Product | (3-{2-[((1R,2S)-2-Hydroxy-indan-1-ylamino)-methyl]-4-trifluoromethyl-phenoxy}-4-methoxy-phenyl)-acetic acid ethyl ester | HCID 58237666 | — |
Reaction Steps
Prepared according to the procedure described in Example 45, Step 3, using the following starting materials: [3-(2-Formyl-4-trifluoromethyl-phenoxy)-4-methoxy-phenyl]-acetic acid ethyl ester and (1R,2S)-(+)-cis-1-amino-2-indanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242145B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-f54eb8ac2bad4a2fa62d741cf36f7c65 |
| Source note | uspto-grants-2012_08 |