反应详情

[3-(4-Bromo-2-bromomethyl-phenoxy)-phenyl]-acetic acid ethyl ester (0.15 g, 0.35 mmol) and 2-pyrrolidinone (0.05 g, 0.53 mmol) were combined in 1,4-dioxane (10 mL). Sodium hydride (60% in mineral oil; 0.03 g, 0.7 mmol) was added, and the reaction was stirred at room temperature for 2 hours to give the title compound, which was used as a crude solution in the hydrolysis step.