2-Imidazolidinone → {3-[4-Bromo-2-(2-oxo-imidazolidin-1-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl ester

HRID 885415Notes

Reaction equation

[CH2:1]([O:3][C:4](=[O:24])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([Br:21])=[CH:17][C:16]=2[CH2:22]Br)[CH:7]=1)[CH3:2].[NH:25]1[CH2:29][CH2:28][NH:27][C:26]1=[O:30]>>[CH2:1]([O:3][C:4](=[O:24])[CH2:5][C:6]1[CH:11]=[CH:10][C:9]([O:12][CH3:13])=[C:8]([O:14][C:15]2[CH:20]=[CH:19][C:18]([Br:21])=[CH:17][C:16]=2[CH2:22][N:25]2[CH2:29][CH2:28][NH:27][C:26]2=[O:30])[CH:7]=1)[CH3:2]

Participants

Reactant 2

HCID 84532-Imidazolidinone

HCID 58237498[3-(4-Bromo-2-bromomethyl-phenoxy)-4-methoxy-phenyl]acetic acid ethyl ester

Product 1

HCID 58237597{3-[4-Bromo-2-(2-oxo-imidazolidin-1-ylmethyl)-phenoxy]-4-methoxy-phenyl}-acetic acid ethyl ester

Procedure

Prepared according to the procedure described in Example 116, Step 1, using the following starting materials: [3-(4-bromo-2-bromomethyl-phenoxy)-4-methoxy-phenyl]acetic acid ethyl ester and 2-imidazolidone.

Workup

customPrepared

Sources & evidence

ORD record: ord-1d32df8c9f37486ab970f157a08ada6e
Source dataset: uspto-grants-2012_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08242145B2

Reaction notes

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