2-(2-Ethyl-4,6-dimethylbenzimidazol-1-yl)methyl-10,11-dihydro-5H-dibenzo[b,f]azepine → HCID 178437439, compound

HRID 885432Notes

Reaction equation

HRID 885432 reaction equation
[CH2:1]([C:3]1[N:7](CC2C=CC3NC4C=CC=CC=4CCC=3C=2)[C:6]2[CH:24]=[C:25](C)[CH:26]=[C:27]([CH3:28])[C:5]=2[N:4]=1)[CH3:2].C(C1[NH:33]C2C(C)=CC(C)=CC=2N=1)C>>[CH2:1]([C:3]1[NH:7][C:6]2=[N:33][C:25]([CH3:24])=[CH:26][C:27]([CH3:28])=[C:5]2[N:4]=1)[CH3:2]

Participants

3

Reactant 2

HCID 690154802-(2-Ethyl-4,6-dimethylbenzimidazol-1-yl)methyl-10,11-dihydro-5H-dibenzo[b,f]azepineHCID 178437417HCID 178437417, compound

Product 1

HCID 178437439HCID 178437439, compound

Procedure

[step 1] 2-(2-Ethyl-4,6-dimethylbenzimidazol-1-yl)methyl-10,11-dihydro-5H-dibenzo[b,f]azepine (422 mg, 75%) was obtained in the same manner as in step 1 of Example 1, using 2-ethyl-4,6-dimethylbenzimidazole (256 mg, 1.47 mmol), obtained in Reference Example 1, instead of 2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine.

Sources & evidence

ORD record
ord-5e856ac07ae641f9b047fbafab891967
Source dataset
uspto-grants-2012_08
Patent number
US08242151B2

Reaction notes

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