HuagongsheHuagongshe Chemistry Print Report · For research reference only
(Z)-2-(8-hydroxymethyl-6,11-dihydrodibenzo[b,e]oxepin-11-ylidene)propiononitrile → HCID 178437439, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (Z)-2-(8-hydroxymethyl-6,11-dihydrodibenzo[b,e]oxepin-11-ylidene)propiononitrile | HCID 67211541 | — |
| Reactant | (Z)-2-[8-(2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl-6,11-dihydrodibenzo[b,e]oxepin-11-ylidene]propiononitrile | HCID 69016353 | — |
| Product | HCID 178437439 | HCID 178437439 | 264% |
Reaction Steps
[step 1] (Z)-2-[8-(2-Ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridin-3-yl)methyl-6,11-dihydrodibenzo[b,e]oxepin-11-ylidene]propiononitrile (158 mg, 57%) was obtained in the same manner as in step 1 of Example 104, using (Z)-2-(8-hydroxymethyl-6,11-dihydrodibenzo[b,e]oxepin-11-ylidene)propiononitrile (178 mg, 0.64 mmol) obtained in Reference Example 31 and 2-ethyl-5,7-dimethyl-3H-imidazo[4,5-b]pyridine (169 mg, 0.96 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242151B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-cc0ba9c04864461b9e1593a593e08089 |
| Source note | uspto-grants-2012_08 |