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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885446Generated: October 30, 2026

(Z)-2-[8-(2-Cyclopropyl-4-methylbenzimidazol-1-yl)methyl-6,11-dihydrodibenzo[b,e]oxepin-11-ylidene]propiononitrile → HCID 178437417, compound

https://huagongshe.com/reaction/885446

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(Z)-2-[8-(2-Cyclopropyl-4-methylbenzimidazol-1-yl)methyl-6,11-dihydrodibenzo[b,e]oxepin-11-ylidene]propiononitrileHCID 69016635—
ReactantHCID 178423935HCID 178423935—
ProductHCID 178437417HCID 178437417—

Reaction Steps

[step 1] (Z)-2-[8-(2-Cyclopropyl-4-methylbenzimidazol-1-yl)methyl-6,11-dihydrodibenzo[b,e]oxepin-11-ylidene]propiononitrile (764 mg, 89%) was obtained in the same manner as in step 1 of Example 140, using 2-cyclopropyl-4-methylbenzimidazole (342 mg, 1.98 mmol), obtained in Reference Example 28, instead of 2-ethyl-4,6-dimethylbenzimidazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242151B2
Source datasetuspto-grants-2012_08
ORD IDord-abf893799efc4db9a95d190ecfb16761
Source noteuspto-grants-2012_08