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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 885533Generated: October 31, 2026

2,2-Difluoro-2-phenylethanol → α,α-Difluorobenzeneacetaldehyde

https://huagongshe.com/reaction/885533

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2-Difluoro-2-phenylethanolHCID 9793891—
Reactant3-(4-Phenylbutoxy)propionaldehydeHCID 86658307—
Productα,α-DifluorobenzeneacetaldehydeHCID 14644933—

Reaction Steps

Obtained from Intermediate 6 (1.0 g, 6.3 mmol) by the procedure described for the Intermediate 13. The title compound was obtained (0.88 g, 86%) as oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242177B2
Source datasetuspto-grants-2012_08
ORD IDord-541a4cc110524f05b479b3d3bf17c768
Source noteuspto-grants-2012_08