HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → 1-(6-Chloropyridin-3-yl)-4-methylpiperazine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | 5-Bromo-2-chloropyridine | HCID 2734414 | — |
| Product | 1-(6-Chloropyridin-3-yl)-4-methylpiperazine | HCID 75355748 | — |
Reaction Steps
The title compound was prepared from 5-bromo-2-chloropyridine and 1-methylpiperazine according to Method BG and was isolated as a brown oil (27%). LCMS (ES+) 212.0 (M+H)+, RT 1.97 minutes (70% purity) (Method 2).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08242116B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-ca10648444af454897bc959cea819a07 |
| Source note | uspto-grants-2012_08 |