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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 886221Generated: October 30, 2026

1-(2-Morpholinoethyl)-1H-pyrazole-4-boronic acid pinacol ester → HCID 58204873, compound

https://huagongshe.com/reaction/886221

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Morpholinoethyl)-1H-pyrazole-4-boronic acid pinacol esterHCID 17749924—
Reactant9-Bromo-2-(1-isopropyl-3-methyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepineHCID 58204322—
ProductHCID 58204873HCID 58204873—

Reaction Steps

Similarly to as described in General Procedure C, 8-Bromo-2-(2-isopropyl-5-methyl-2H-[1,2,4]triazol-3-yl)-4,5-dihydro-6-oxa-1,3a-diaza-benzo[e]azulene was reacted with 4-(2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazol-1-yl)ethyl)morpholine. Purification of the crude reaction mixture by reverse phase HPLC gave 210. LCMS: 489.2

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08242104B2
Source datasetuspto-grants-2012_08
ORD IDord-9d9df9252c0647e0ae466ff00e007a17
Source noteuspto-grants-2012_08