Hydrogen chloride-ethyl acetate → HCID 68579793, compound

Participants

Reaction Steps

A solution of tert-butyl 9-(piperidin-1-yl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate (130 mg, 0.391 mmol) and 4N hydrogen chloride-ethyl acetate (4 ml) in ethyl acetate (1 ml) was stirred for 1 hr at room temperature, and the solvent was evaporated under reduced pressure. The residue was recrystallized from a mixed solvent of methanol and ether to give the desired product (93.6 mg, 78.7%) as a solid.

Provenance & Evidence