Hydrogen chloride-ethyl acetate → HCID 86640605, compound

Participants

Reaction Steps

A mixture of tert-butyl 9-bicyclo[2.2.1]hepta-2-yl-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate (100 mg, 0.292 mmol), ethyl acetate (1 ml) and 4N hydrogen chloride-ethyl acetate solution (2 ml) was stirred at room temperature for 0.5 hr, and the solvent was evaporated under reduced pressure. The residue was recrystallized from a mixed solvent of methanol and ether to give the desired product (24.0 mg, 29.4%) as a solid.

Provenance & Evidence