Hydrogen chloride-ethyl acetate → HCID 68580146, compound

Participants

Reaction Steps

A mixture of tert-butyl 9-(3,5-dimethylisoxazol-4-yl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate (120 mg, 0.348 mmol), ethyl acetate (1 ml) and 4N hydrogen chloride-ethyl acetate solution (2 ml) was stirred at room temperature for 1 hr, and the solvent was evaporated under reduced pressure. The residue was recrystallized from a mixed solvent of methanol and ether to give the desired product (67.4 mg, 69.0%) as a solid.

Provenance & Evidence