Hydrogen chloride-ethyl acetate → HCID 68580168, compound

Participants

Reaction Steps

A mixture of tert-butyl 9-(3-fluorophenyl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate (390 mg, 1.14 mmol), ethyl acetate (4 ml) and 4N hydrogen chloride-ethyl acetate solution (4 ml) was stirred at room temperature for 1 hr, and the solvent was evaporated under reduced pressure. The residue was recrystallized from a mixed solvent of methanol and ether to give the desired product (309 mg, 97.2%) as a solid.

Provenance & Evidence