Hydrogen chloride-ethyl acetate → HCID 68578461, compound

Participants

Reaction Steps

A mixture of tert-butyl 9-(2-oxo-1,3-oxazolidin-3-yl)-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate (230 mg, 0.688 mmol), ethyl acetate (3 ml) and 4N hydrogen chloride-ethyl acetate solution (3 ml) was stirred at room temperature for 1 hr, and the solvent was evaporated under reduced pressure. The residue was recrystallized from a mixed solvent of methanol and ether to give the desired product (118 mg, 63.4%) as a solid.

Provenance & Evidence