Hydrogen chloride-ethyl acetate → HCID 68578312, compound

Participants

Reaction Steps

A mixture of tert-butyl 9-cyclobutyl-2,3-dihydro-1,4-benzoxazepine-4(5H)-carboxylate (40.0 mg, 0.132 mmol), ethyl acetate (2 ml) and 4N hydrogen chloride-ethyl acetate solution (2 ml) was stirred at room temperature for 1 hr, and the solvent was evaporated under reduced pressure. The residue was recrystallized from a mixed solvent of methanol and ether to give the desired product (25.0 mg, 79.1%) as a solid.

Provenance & Evidence