HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → Cyclopropyl(4-(trifluoromethyl)phenyl)methanamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | Cyclopropyl 4-trifluoromethylphenyl ketone | HCID 11171894 | — |
| Product | Cyclopropyl(4-(trifluoromethyl)phenyl)methanamine | HCID 22337655 | — |
Reaction Steps
The title compound was prepared using the product from Example 141B and the procedures described in Examples 136A and 136B. 1H NMR (300 MHz, d6-DMSO) 7.92 (m, 4H), 3.24 (d, 1H), 1.92 (broad s, 2H), 0.93 (m, 1H), 0.50-0.27 (m, 4H); MS (DCI/NH3) m/e 216 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08247413B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-17001ddf94954b7b855fc2e28e9e5933 |
| Source note | uspto-grants-2012_08 |