HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → 2-(4-Chlorophenyl)-2-methylpropanoyl chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | 2-(4-Chlorophenyl)-2-methylpropionic acid | HCID 80406 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 2-(4-Chlorophenyl)-2-methylpropanoyl chloride | HCID 13536863 | — |
Reaction Steps
2-(4-Chlorophenyl)-2-methylpropanoic acid (3.85 g, 19.4 mmol) in toluene (5 mL) and thionyl chloride (5.00 g, 3.1 mL) was heated at 80° C. for 2 hours. The mixture was cooled and concentrated under reduced pressure to provide the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08247413B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-86526bc526fa45dd831ddd12ca5f66e9 |
| Source note | uspto-grants-2012_08 |