Water → 7-chloro-8-fluoro-5-methyl-6-oxo-5,6-dihydro-4H-imidazo[1,5-a][1,4]benzodiazepine-3-carbonitrile
Reaction equation
[Cl:1][c:2]1[c:3]([F:21])[cH:4][cH:5][c:6]2[c:7]1[C:8](=[O:20])[N:9]([CH3:19])[CH2:10][c:11]1[n:12]-2[cH:13][n:14][c:15]1[C:16](=[O:17])[NH2:18].[F:28][C:29]([F:30])([F:31])[C:32]([O:33][C:34](=[O:35])[C:36]([F:37])([F:38])[F:39])=[O:40].[O:42]1[CH2:43][CH2:44][O:45][CH2:46][CH2:47]1.[OH2:41].[cH:22]1[cH:23][cH:24][n:25][cH:26][cH:27]1>>[Cl:1][c:2]1[c:3]([F:21])[cH:4][cH:5][c:6]2[c:7]1[C:8](=[O:20])[N:9]([CH3:19])[CH2:10][c:11]1[n:12]-2[cH:13][n:14][c:15]1[C:16]#[N:18]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-4e836d9a3e4944ed9ff96643a3291007
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
Loading…