HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 887775Generated: October 30, 2026
Hydrochloric Acid → 2-(8,9-dihydro-7H-cyclopenta[c]pyrazolo[1,5-a]pyridin-9-yl)ethanamine hydrochloride
https://huagongshe.com/reaction/887775
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | ethyl 9-(2-aminoethyl)-8,9-dihydro-7H-cyclopenta[c]pyrazolo[1,5-a]pyridine-1-carboxylate | HCID 59145841 | — |
| Product | 2-(8,9-dihydro-7H-cyclopenta[c]pyrazolo[1,5-a]pyridin-9-yl)ethanamine hydrochloride | HCID 68698916 | 99% |
Reaction Steps
A mixture of ethyl 9-(2-aminoethyl)-8,9-dihydro-7H-cyclopenta[c]pyrazolo[1,5-a]pyridine-1-carboxylate (105 mg, 0.384 mmol) in 12M hydrochloric acid (4 mL) was stirred at 110° C. for 14 hr, and concentrated under reduced pressure to give the title compound (91.1 mg, yield 99%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08247429B2 |
|---|
| Source dataset | uspto-grants-2012_08 |
|---|
| ORD ID | ord-1749d3fff6284c948d5d28fb15940750 |
|---|
| Source note | uspto-grants-2012_08 |
|---|
