HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 887777Generated: October 30, 2026
Hydrochloric Acid → 2-(2-methyl-8,9-dihydro-7H-cyclopenta[c]pyrazolo[1,5-a]pyridin-9-yl)ethanamine hydrochloride
https://huagongshe.com/reaction/887777
Participants
| Role | Name | HCID | Charge |
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| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | ethyl 9-(2-aminoethyl)-2-methyl-8,9-dihydro-7H-cyclopenta[c]pyrazolo[1,5-a]pyridine-1-carboxylate | HCID 59145868 | — |
| Product | 2-(2-methyl-8,9-dihydro-7H-cyclopenta[c]pyrazolo[1,5-a]pyridin-9-yl)ethanamine hydrochloride | HCID 68701819 | — |
Reaction Steps
A mixture of ethyl 9-(2-aminoethyl)-2-methyl-8,9-dihydro-7H-cyclopenta[c]pyrazolo[1,5-a]pyridine-1-carboxylate (140 mg, 0.487 mmol) in 12M hydrochloric acid (5 mL) was stirred at 100° C. for 2 days, and concentrated under reduced pressure to give the title compound. The obtained title compound was used for the reaction of Example 18 without purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08247429B2 |
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| Source dataset | uspto-grants-2012_08 |
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| ORD ID | ord-3d680b3ea20444e5b5da2c6d75f679d6 |
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| Source note | uspto-grants-2012_08 |
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