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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 888082Generated: November 1, 2026

HCID 22249227, compound → tert-Butyl 4-(5-amino-2-(perfluoroethyl)benzyl)piperazine-1-carboxylate

https://huagongshe.com/reaction/888082

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 22249227HCID 22249227—
Reactant4-Pentafluoroethyl-3-(2-pyrrolidin-1-yl-ethoxy)-phenylamineHCID 86002232—
Producttert-Butyl 4-(5-amino-2-(perfluoroethyl)benzyl)piperazine-1-carboxylateHCID 86614208—

Reaction Steps

tert-Butyl 4-(5-amino-2-(perfluoroethyl)benzyl)piperazine-1-carboxylate was prepared from 1-Boc-4-(5-nitro-2-pentafluoroethyl-benzyl)-piperazine similar to that described in the preparation of 4-pentafluoroethyl-3-(2-pyrrolidin-1-yl-ethoxy)-phenylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08247556B2
Source datasetuspto-grants-2012_08
ORD IDord-eb2e6dd462764447b8ee309c8ece36dd
Source noteuspto-grants-2012_08