HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Aminomethyl-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-oxo-1H,2H,3H-pyrrolo[2,3-b]pyridine-4-carbonitrile | HCID 69263796 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 4-Aminomethyl-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one hydrochloride | HCID 69269059 | — |
Reaction Steps
Hydrogenation of 2-Oxo-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-4-carbonitrile (100 mg) was done using Pd/C (20 mg), HCl (37%, 0.3 mL) in EtOH (3 mL) to give 4-aminomethyl-1,3-dihydro-pyrrolo[2,3-b]pyridin-2-one hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08247556B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-9daf00d2886849808144e9814dad16c1 |
| Source note | uspto-grants-2012_08 |