HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(4,4-dimethyl-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide → N-(4,4-Dimethyl-1,2,3,4-tetrahydroquinolin-7-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(4,4-dimethyl-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide | HCID 68908856 | — |
| Reactant | (1h-Pyrrolo[2,3-b]pyridin-4-yl)methanamine dihydrochloride | HCID 69263704 | — |
| Product | N-(4,4-Dimethyl-1,2,3,4-tetrahydroquinolin-7-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide | HCID 58942005 | — |
Reaction Steps
The titled compound was prepared from N-(4,4-dimethyl-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide and C-(1H-pyrrolo[2,3-b]pyridin-4-yl)-methylamine dihydrochloride by the method described in Step A of Example 1. MS (ES+): 427 (M+H). Calc'd. for C25H26N6O—426.52.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08247556B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-71c2b2445fba460ba9ff8c03bc7edf58 |
| Source note | uspto-grants-2012_08 |