HuagongsheHuagongshe Chemistry Print Report · For research reference only
N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide → N-(4,4-Dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide | HCID 21961472 | — |
| Reactant | (1h-Pyrrolo[2,3-b]pyridin-4-yl)methanamine dihydrochloride | HCID 69263704 | — |
| Product | N-(4,4-Dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)-2-[(1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]nicotinamide | HCID 58941984 | — |
Reaction Steps
The titled compound was prepared from N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide and C-(1H-pyrrolo[2,3-b]pyridin-4-yl)-methylamine dihydrochloride by the method described in Step A of Example 1. MS (ES+): 441 (M+H). Calc'd. for C25H24N6O2—440.51.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08247556B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-f0c62ea340624e4b9a49d144843b8990 |
| Source note | uspto-grants-2012_08 |