N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide → 2-[(2,3-Dihydro-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]-N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)nicotinamide

Participants

Role	Name	HCID	Charge
Reactant	N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide	HCID 21961472	—
Reactant	C-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-4-yl)-methylamine dihydrochloride	HCID 69263942	—
Product	2-[(2,3-Dihydro-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]-N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)nicotinamide	HCID 16225422	—

Reaction Steps

The titled compound was prepared from N-(4,4-dimethyl-2-oxo-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide and C-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-4-yl)-methylamine dihydrochloride by the method described in Step A of Example 1. MS (ES+): 437 (M+H). Calc'd. for C25H26N6O2—442.52.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08247556B2
Source dataset	uspto-grants-2012_08
ORD ID	ord-c953c2bdbbfe4bf3b9aac297ad71ee89
Source note	uspto-grants-2012_08