N-(4,4-dimethyl-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide → 2-[(2,3-Dihydro-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]-N-(4,4-dimethyl-1,2,3,4-tetrahydroquinolin-7-yl)nicotinamide

Participants

Role	Name	HCID	Charge
Reactant	N-(4,4-dimethyl-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide	HCID 68908856	—
Reactant	C-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-4-yl)-methylamine dihydrochloride	HCID 69263942	—
Product	2-[(2,3-Dihydro-1H-pyrrolo[2,3-b]pyridin-4-ylmethyl)amino]-N-(4,4-dimethyl-1,2,3,4-tetrahydroquinolin-7-yl)nicotinamide	HCID 16224617	—

Reaction Steps

The titled compound was prepared from N-(4,4-dimethyl-1,2,3,4-tetrahydro-quinolin-7-yl)-2-fluoro-nicotinamide and C-(2,3-dihydro-1H-pyrrolo[2,3-b]pyridin-4-yl)-methylamine dihydrochloride by the method described in Step A of Example 1. MS (ES+): 429 (M+H). Calc'd. for C25H28N6O—428.54.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US08247556B2
Source dataset	uspto-grants-2012_08
ORD ID	ord-b4767d56b415424f8b578d92cb86f65b
Source note	uspto-grants-2012_08