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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 888171Generated: November 1, 2026

(3R)-3-methyl-1-pyridin-2-ylpiperazine → (3S)-3-methyl-1-pyridin-2-ylpiperazine

https://huagongshe.com/reaction/888171

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(3R)-3-methyl-1-pyridin-2-ylpiperazineHCID 1519493—
Reactant2-Methylpiperazine, (S)-HCID 2734219—
SolventChloroform methanolHCID 21584188—
Product(3S)-3-methyl-1-pyridin-2-ylpiperazineHCID 1519492—

Reaction Steps

The title compound was prepared following the protocol used for the preparation of Intermediate 3, but starting from (S)-2-methyl piperazine (43%). TLC-Chloroform/MeOH (8/2); Rf=0.2.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08247437B2
Source datasetuspto-grants-2012_08
ORD IDord-670aadbaf3eb4fbcbaed95bc018bbae5
Source noteuspto-grants-2012_08