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HRID888185

反应详情

EQUATION

反应方程式

HRID 888185 的结构方程式

REACTANTS

反应物

2
结构：Brc1ccc(Br)nc1
HCID69353

2,5-Dibromopyridine

C5H3Br2N

结构：C[C@@H]1CN(c2ccc(C(F)(F)F)cn2)CCN1
HCID26597358

未命名化合物

PRODUCTS

生成物

1
结构：Brc1ccc(N2CCNCC2)nc1
HCID16414227

1-(5-Bromopyridin-2-yl)piperazine

C9H12BrN3

收率 73%

PROCEDURE

实验过程

The title compound was prepared following the procedure of the Intermediate 15, but starting from 2,5-dibromopyridine. Purification by chromatography (DCM/MeOH 80/20) gave the title compound as a brown powder (73%). M+(ESI): 244.2. HPLC (Condition A), Rt: 1.1 min (HPLC purity: 79.7%).

WORKUP

后处理

  1. customThe title compound was prepared
  2. customPurification by chromatography (DCM/MeOH 80/20)