HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 68500068, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 68499410 | HCID 68499410 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 68500068 | HCID 68500068 | — |
Reaction Steps
To a DCM (22 mL) solution tert-butyl 4′-methyl-5-(2,2,2-trifluoro-1-hydroxyethyl)biphenyl-3-carboxylate (1.6 g, 4.4 mmol) from step A was added trifluoroacetic acid (22 mL). The mixture was stirred at rt for 3 h and concentrated to dryness. The crude title compound was used in step C without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08247401B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-a5c9e3bae91a4826835e10116b13f0e5 |
| Source note | uspto-grants-2012_08 |