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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 8884Generated: October 27, 2026

2,2,2-Trifluoroethyl Methanesulfonate → 2-Methyl-4-[2-methyl-1-(2,2,2-trifluoro-ethyl)-1H-imidazol-4-ylethynyl]-pyridine

https://huagongshe.com/reaction/8884

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2,2-Trifluoroethyl MethanesulfonateHCID 556565—
ReactantHCID 178418884HCID 178418884—
Product2-Methyl-4-[2-methyl-1-(2,2,2-trifluoro-ethyl)-1H-imidazol-4-ylethynyl]-pyridineHCID 11265935—

Reaction Steps

The title compound, MS: m/e=280.1 (M+H+), was prepared in accordance with the general method of example 1 from 2-methyl-4-(2-methyl-1H-imidazol-4-ylethynyl)-pyridine and 2,2,2-trifluoroethyl mesylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07091222B2
Source datasetuspto-grants-2006_08
ORD IDord-08a2d881db674a16b9f53b7e318f89a5
Source noteuspto-grants-2006_08