Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | Methyl 3-(5-chloropyridin-2-yl)-5-isopropenylbenzoate | HCID 68497736 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Sodium Chloride | HCID 5234 | — |
| Product | 3-(5-Chloropyridin-2-yl)-5-isopropenylbenzoic acid | HCID 68501347 | — |
Reaction Steps
To a solution of methyl 3-(5-chloropyridin-2-yl)-5-isopropenylbenzoate (0.13 g, 0.46 mmol) in methanol (3.1 mL) was added 1 M aqueous sodium hydroxide (0.92 mL, 0.92 mmol) and the mixture was heated to 60° C. After 45 min, hydrochloric acid (76 uL, 092 mmol) was added and the mixture was concentrated to dryness gave the bis sodium chloride salt of the title compound. MS 274.0 (M+1).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08247401B2 |
|---|
| Source dataset | uspto-grants-2012_08 |
|---|
| ORD ID | ord-3b6c819b53874c38b6a7d7426d144e00 |
|---|
| Source note | uspto-grants-2012_08 |
|---|
