反应详情

温度

60 °C

To a solution of methyl 3-(5-chloropyridin-2-yl)-5-isopropenylbenzoate (0.13 g, 0.46 mmol) in methanol (3.1 mL) was added 1 M aqueous sodium hydroxide (0.92 mL, 0.92 mmol) and the mixture was heated to 60° C. After 45 min, hydrochloric acid (76 uL, 092 mmol) was added and the mixture was concentrated to dryness gave the bis sodium chloride salt of the title compound. MS 274.0 (M+1).

1. concentrationthe mixture was concentrated to dryness