HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Hydroxybenzotriazole → HCID 17796731, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Hydroxybenzotriazole | HCID 75771 | — |
| Reactant | Methanamine, N-methoxy-, hydrochloride (1:1) | HCID 81138 | — |
| Reactant | 3,4,5-Trifluorobenzoic acid | HCID 853154 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 17796731 | HCID 17796731 | — |
Reaction Steps
Following the procedure of Example 29, step (b), reaction of 3,4,5-trifluoro-benzoic acid with N,O-dimethylhydroxylamine HCl in present of HOBT, EDA, TEA in DCM followed the column purification gave the title compound; Calcd MW 219.16. Found MH+ 220.1.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08247610B2 |
| Source dataset | uspto-grants-2012_08 |
| ORD ID | ord-11793d4295e6458eafce0552834019dc |
| Source note | uspto-grants-2012_08 |