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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 888712Generated: October 31, 2026

Sodium borohydride → 2-(2-methyl-phenyl)-N-methyl-2-hydroxy-acetamide

https://huagongshe.com/reaction/888712

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium borohydrideHCID 4311764—
ReactantN-methyl-2-(2-methylphenyl)-2-oxoacetamideHCID 15239356—
SolventMethanolHCID 887—
Product2-(2-methyl-phenyl)-N-methyl-2-hydroxy-acetamideHCID 66936442—

Reaction Steps

Racemic 2-(2-methyl-phenyl)-N-methyl-2-hydroxy-acetamide was synthesized by reducing 2-(2-methyl-phenyl)-N-methyl-2-oxo-acetamide with NaBH4 in methanol.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08252563B2
Source datasetuspto-grants-2012_08
ORD IDord-003b3cf8705c4510a16aa3f43ef3d674
Source noteuspto-grants-2012_08